UC DAVIS GENERAL CATALOG--Programs and Courses

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Biological Chemistry (BCM)

Upper Division Courses Graduate Courses Professional Courses

*Course not offered this academic year.

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Lower Division Course

92. Internship in Biological Chemistry (1-12) I, II, III, IV. The Staff

Internship--3-36 hours; final report. Prerequisite: consent of instructor. Supervised work experience in biological chemistry and related fields. (P/NP grading only.)

Upper Division Courses

*131. Introduction to Magnetic Resonance in Biology (2) III. Jue

Lecture--2 hours. Prerequisite: Chemistry 8B or 118B or 128B. Fundamental concepts in magnetic resonance and their application to protein structure determination. Theoretical and experimental methods. Two-dimensional NMR techniques. Offered in alternate years.

192. Internship in Biological Chemistry (1-12) I, II, III, IV. The Staff

Internship--3-36 hours; final report. Prerequisite: upper division standing; approval of project prior to internship by preceptor. Supervised work experience in Biological Chemistry and related fields. (P/NP grading only.)

198. Group Study (1-5) I, II, III, IV. The Staff

Prerequisite: consent of instructor. For undergraduate students desiring to explore particular topics in depth. Lectures and conferences may be involved. (P/NP grading only.)

199. Special Study for Advanced Undergraduates (1-5) I, II, III, IV. The Staff

Prerequisite: consent of instructor. (P/NP grading only.)

Graduate Courses

209. Prostaglandins/Leukotrienes and Related Lipids (2) II. Ziboh (Dermatology)

Lecture--2 hours. Prerequisite: Biochemistry 101A-101B or Physiological Sciences 101A-101B or Physiology 100A-100B. Oxidative desaturation/elongation of poyunsaturated fatty acids. Biosynthesis of prostaglandins/leukotrienes from polyunsaturated fatty acids. Chemistry, biochemistry, and metabolism. Nutritional regulation. Physiological/pathophysiological implications; pharmacological and clinical relevance. Offered in alternate years.

214. Molecular Medicine (1) II. Seldin

Discussion--1 hour. Prerequisite: course in biochemistry or the equivalent. Series of lectures on current topics of biochemistry related to medicine. Material covered stresses concepts derived from biochemical research which have some potential clinical relevance. (S/U grading only.) (Same course as 414.)

*217. Molecular Genetics of Fungi (3) II. Holland

Lecture--3 hours. Prerequisite: graduate standing in a biological science; Biochemistry 101B; Genetics 100, 102A; Botany 119; Plant Pathology 130, 215X; Microbiology 215 recommended. Advanced treatment of molecular biology and genetics of filamentous fungi and yeasts, including gene structure, organization and regulation; secretion; control of reproduction; molecular evolution; transformation; and gene manipulation. Offered in alternate years. (Same course as Plant Pathology 217.)

222. Mechanisms of Translational Control (2) II. Hershey

Lecture--1 hour; discussion--1 hour. Prerequisite: Biochemistry 201C or consent of instructor. Molecular mechanisms of protein synthesis and translational control in eucaryotic cells, with emphasis on mammalian cells and their viruses. An advanced graduate-level treatment of topics of current interest, with readings and discussion of primary papers from the literature. Offered in alternate years.

230. Practical NMR Spectroscopy and Imaging (1) I. The Staff

Lecture--1 hour. Prerequisite: Chemistry 107A-107B, Physics 5A-5B-5C or 9A-9B-9C, or consent of instructor. Basic theory, experimental methods, and instrumentation of NMR. Enables students to understand NMR spectroscopy and imaging experiments. (S/U grading only.)

*231. Biological Nuclear Magnetic Resonance (3) III. Jue

Lecture--3 hours. Prerequisite: Molecular and Cellular Biology 221A or the equivalent or consent of instructor. Principles and applications of magnetic resonance in biomedicine. Fundamental concepts and the biophysical basis for magnetic resonance applications in areas of tissue characterization/imaging, metabolic regulation, and cellular bioenergetics. Offered in alternate years. (Same course as Biophysics 231.)

298. Group Study (1-5) I, II, III, IV. The Staff

Prerequisite: consent of instructor. For graduate students desiring to explore particular topics in depth. Lectures and conferences may be involved.

299. Research (1-12) I, II, III, IV. The Staff

Prerequisite: consent of instructor. (S/U grading only.)

Professional Courses

410A. Molecular and Cell Biology (4.5) I. Matthews, Holland

Lecture--5 hours. Prerequisite: approval by Committee on Student Evaluation and Promotion. Basic biochemistry of proteins and nucleic acids is presented, followed by molecular genetics, regulation of gene expression, enzymes and structural proteins. Applications to clinically relevant systems are emphasized, particularly sickle cell anemia, thalassemias, immunoglobulins and monoclonal antibodies, oncogenes, cell proliferation control.

410B. Cell Biology and Metabolism (3.5) II. Jue

Lecture--4 hours (for 9 weeks). Prerequisite: approval by Committee on Student Evaluation and Promotion. Introduction to transport of small molecules and ions across membranes is followed by study of energy metabolism and biosynthetic processes in humans. Membrane receptors are considered as they relate to basic metabolic processes. Correlations to human disease are made throughout.

414. Molecular Medicine (1) II. Seldin

Discussion--1 hour. Prerequisite: course in biochemistry or the equivalent. Series of lectures on current topics of biochemistry related to medicine. Material covered stresses concepts derived from biochemical research which have some potential clinical relevance, and are intended to be of interest to medical students. (S/U grading only.) (Same course as 214.)

418. Mammalian Endocrinology and Homeostasis (4.5) III. Walsh and staff

Lecture--4 hours; discussion--1 hour; student presentation. Prerequisite: approval by Committee on Student Evaluation and Promotion. Physiological and biochemical properties of the mammalian endocrine system at both the cellular and systemic level. Principles that regulate homeostasis, especially in organ-organ interrelationships, metabolites, and minerals. Reproductive endocrinology. (Same course as Human Physiology 418.)

419. Introduction to Clinical Nutrition (3) III. Phinney (Internal Medicine, Clinical Nutrition and Metabolism), Rucker, and staff

Lecture--5 hours; lecture/discussion--1.5 hours; laboratory/discussion--0.5 hour (for 4 weeks). Prerequisite: approval by Committee on Student Evaluation and Promotion. A 28-hour course that integrates basic and clinical concepts of human nutrition. The course emphasizes nutrient homeostasis and regulation and current perspectives on the role of nutrition in disease. Format is partly lectures, partly discussion/case study. (Same course as Internal Medicine 419.)

497T. Tutoring in Biological Chemistry (1-5) I, II, III, IV. The Staff

Tutoring--3-15 hours. Prerequisite: advanced standing or consent of instructor. Assist instructor by tutoring medical students in preparation for one of the departmental courses that is a component of the required curriculum of the School of Medicine. (S/U grading only.)

498. Group Study (1-5) I, II, III, IV. The Staff (Chairperson in charge)

Prerequisite: medical students with consent of instructor. (S/U grading only.)

499. Research (1-12) I, II, III, IV. The Staff (Chairperson in charge)

Prerequisite: medical students with consent of instructor. (S/U grading only.)


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UC Davis 1997-98 Online General Catalog. Posted August 1, 1997.
catalog-comment@ucdavis.edu
Keitha Hunter and Barbara Anderson, Editors

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